Spectrum of Aspergillus infections in post TB patients

Abstract

Background: Fungal colonisation of airways in Post TB patients, can lead to a spectrum of diseases based on the immune
response of the host. This study was aimed at studying the different entities of this spectrum. Methods: A cross sectional
observational study was conducted over 100 patients of post TB patients to make an observation of the diseases of the
spectrum of Aspergillus infections. Results: Of the 100 patients who were studied, IPA was found in 24 (48%), ABPA in
13(26%), CPA in 5(10%) patients out of the 50 diabetics. ABPA in 23 (46%) patients, Simple colonization, CPA in
11(22%) and 4 (8%) patients showed IPA out of the 50 non-diabetics. Conclusion: Chronic pulmonary Aspergillosis was
the most common disease from Aspergillus among Post TB patients. Diabetes was associated to invasive forms of
Aspergillosis, Invasive Pulmonary aspergillosis (IPA) and subacute invasive pulmonary aspergillosis (SAIA).