Effectiveness of Atorvastatin in the Management of Hypercholesterolemia

Authors

  • Sunil Kumar
  • Piyush Yadav
  • L.P. Meena
  • Binay Sen
  • Aparnesh Pandey

Keywords:

High Cholesterol, hypercholesterolemia, lipid profile, Atorvastatin, Clinical trial,

Abstract

Introduction- India is currently undergoing a significant transformation in its epidemiological landscape as a
result of variables such as population growth, economic progress, urbanization, and an aging population, all of
which contribute to alterations in risk factors. The increase in cardiovascular risk and hypercholesterolemia is
associated with the adoption of unfavorable lifestyles. Statins are used very commonly as lipid-lowering
medications.. Although statins have proven to be helpful, additional research is required to fully comprehend
their efficacy, potential negative effects, and long-term toxicity. Methodology-A study was carried out at SS
Hospital, IMS, BHU, Varanasi to evaluate the impact of Atorvastatin treatment on Hypercholesterolemia.
This study focused on persons who were visiting the outpatient department (OPD) of the Modern Medicine
hospital. The intervention was conducted within the hospital setting. Result and Discussion- The consistent
and comparable triglyceride/LDL cholesterol reduction was observed after treatment with Atorvastatin. No
major side effects were observed on biochemical tests, like LFT and KFT over 90-day follow up. A long term
follow up and histological examination, either invasive of non-invasive, is required to give conclusive report.

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Published

2024-09-11

How to Cite

Kumar, S., Yadav, P., Meena, L., Sen, B., & Pandey, A. (2024). Effectiveness of Atorvastatin in the Management of Hypercholesterolemia . Indian Journal of Preventive & Social Medicine, 55(3), 154–159. Retrieved from http://ijpsm.co.in/index.php/ijpsm/article/view/366