Clinico-epidemiological profile of COVID-19 patients admitted in a tertiary care center in Central India

Abstract

Introduction: India is the second country with the highest Coronavirus Disease-2019 (COVID-19) case burden in the
world. In India, Maharashtra state has the highest number of cases. During September 2020, more than 37% of new
fatalities reported are from Maharashtra. Objective: To study the clinic-epidemiological profile of COVID-19 patients
admitted in a COVID-19 designated tertiary care centre in Central India. Materials and Methods: This is a record based
cross‑sectional study. The epidemiological, demographic, clinical, laboratory, radiological and treatment data of195Real
Time-Polymerase Chain Reaction (RT-PCR) confirmed COVID-19 patients during September 2020 was collected.
Results: Among the 195 laboratory confirmed COVID-19 patients, majority of the patients belonged to the age group of
above 60 years. The most common co-morbid condition found was hypertension followed by diabetes mellitus. The most
common symptoms were breathlessness and fever followed by cough. The mean time from the onset of symptoms to
hospital admission for discharged is more than death cases. In summary, parameters such as lower SpO2, higher TLC,
granulocyte percentage, inflammatory markers (CRP, ferritin), urea, creatinine, liver enzymes, and LDH were
significantly associated with poorer outcomes in COVID-19 patients. Patients aged more than 60 years and patients
associated with comorbidities are more prone for severe disease with Severe Acute Respiratory SyndromeCoronavirus 2
(SARS-CoV-2) pneumonia and this subset of patients requires urgent medical attention.